Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

44.1K
Overview
44.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8<sup>+</sup> T-cell response.

Cellular & molecular immunology·2026
Same author

Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF.

Nature immunology·2025
Same author

Author Correction: DC subsets and states unraveled across human juxtatumoral and malignant tissues.

Nature immunology·2025
Same author

Oncofetal reprogramming of malignant seeds and their ecosystem: Implications in clinical research.

Cancer cell·2025
Same author

Innate type 2 lymphocytes trigger an inflammatory switch in alveolar macrophages.

Immunity·2025
Same author

Novae: a graph-based foundation model for spatial transcriptomics data.

Nature methods·2025
Same journal

Projected health and economic impact of PCV20 vaccination in UK children: a dynamic transmission model.

Expert review of vaccines·2026
Same journal

Evaluating the societal value of adult respiratory vaccination in Sweden: a benefit-cost analysis.

Expert review of vaccines·2026
Same journal

Evaluating the socioeconomic value of adult respiratory immunization in Spain: a benefit-cost analysis.

Expert review of vaccines·2026
Same journal

Whole cell and acellular pertussis vaccines - rethinking the evidence.

Expert review of vaccines·2026
Same journal

Modeling the potential public health and economic impact and cost-effectiveness of vaccination strategies using an adapted COVID-19 vaccine in the Dominican Republic.

Expert review of vaccines·2026
Same journal

Narrative shielding and prebunking: a synergistic strategy against vaccine hesitancy in pediatrics.

Expert review of vaccines·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
10:35

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

3.0K

CD11b+ DCs rediscovered: implications for vaccination.

Florent Ginhoux1, Andreas Schlitzer

  • 1Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, 138648, Singapore.

Expert Review of Vaccines
|February 26, 2014
PubMed
Summary
This summary is machine-generated.

Dendritic cells (DCs) are key immune cells that sense antigens and initiate immune responses. Understanding the diverse subsets of DCs is crucial for developing advanced vaccination strategies.

More Related Videos

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
12:54

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells

Published on: May 19, 2023

2.6K
Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

11.1K

Related Experiment Videos

Last Updated: May 2, 2026

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
10:35

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

3.0K
Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
12:54

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells

Published on: May 19, 2023

2.6K
Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

11.1K

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Dendritic cells (DCs) are critical antigen-presenting cells that initiate and regulate immune responses.
  • DCs recognize pathogens, self-antigens, and vaccine components, influencing immune response type, magnitude, and specificity.

Discussion:

  • The DC population is highly heterogeneous, comprising subsets with distinct ontogeny, differentiation pathways, and specialized functions.
  • Understanding these DC subsets is essential for effective immune modulation.

Key Insights:

  • DCs are versatile immune regulators capable of orchestrating complex adaptive immunity.
  • The functional specialization of DC subsets dictates the nature of the immune response.

Outlook:

  • Further research into DC subset biology will drive the development of novel and more effective vaccination strategies.
  • Targeting specific DC subsets holds promise for enhancing vaccine efficacy and therapeutic immunity.