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Updated: May 2, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Myocardial revascularization strategies in diabetic patients with multi-vessel disease: CABG vs DES-based PCI
George Kassimis, Niket Patel, Adrian P Banning1
1Oxford Heart Centre, John Radcliffe Hospital, Oxford, OX3 9DU, UK. gksup@yahoo.gr.
Insights
Coronary artery bypass grafting (CABG) offers superior long-term outcomes compared to multi-vessel percutaneous coronary intervention for diabetic patients. CABG reduces mortality, heart attacks, and repeat procedures in this population.
Area of Science:
- Cardiology
- Vascular Surgery
Background:
- Diabetic patients with multi-vessel coronary artery disease (CAD) present unique management challenges.
- Long-term outcomes data comparing revascularization strategies are crucial for this high-risk group.
Purpose of the Study:
- To review current management strategies for diabetic patients with multi-vessel CAD.
- To synthesize evidence comparing percutaneous coronary intervention (PCI) and CABG in this population.
Main Methods:
- Review of randomized controlled trials comparing multi-vessel PCI versus CABG.
- Analysis of long-term outcomes including survival, myocardial infarction, and repeat interventions.
Main Results:
- Coronary artery bypass grafting (CABG) demonstrates long-term superiority over multi-vessel PCI in diabetic patients.
- CABG is associated with improved survival rates.
- Patients undergoing CABG experience fewer recurrent myocardial infarctions and a lower need for repeat interventions.
Conclusions:
- CABG remains the preferred revascularization strategy for diabetic patients with multi-vessel CAD.
- Optimal management requires careful consideration of long-term benefits and risks.
Abstract:
Randomized trials comparing multi-vessel percutaneous coronary intervention to coronary artery bypass grafting (CABG) have demonstrated the long-term superiority of CABG in diabetic patients. Benefits include improved survival, fewer recurrent myocardial infarctions and a lower risk of the need for repeat intervention. The focus of this review article is to review the contemporary management of diabetic patients with multi-vessel coronary artery disease.
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