Related Experiment Video For Acetate
Updated: May 2, 2026

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
Published on: January 31, 2025
Acetate/acetyl-CoA metabolism associated with cancer fatty acid synthesis: overview and application
Yukie Yoshii1, Takako Furukawa1, Tsuneo Saga1
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan.
Abstract:
Understanding cancer-specific metabolism is important for identifying novel targets for cancer diagnosis and therapy. Induced acetate/acetyl CoA metabolism is a notable feature that is related to fatty acid synthesis supporting tumor growth. In this review, we focused on the recent findings related to cancer acetate/acetyl CoA metabolism. We also introduce [1-¹¹C]acetate positron emission tomography (PET), which is a useful tool to visualize up-regulation of acetate/acetyl CoA metabolism in cancer, and discuss the utility of [1-¹¹C]acetate PET in cancer diagnosis and its application to personalized medicine.
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