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Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
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The aortic valve: structure, complications and implications for transcatheter aortic valve replacement

Mm Rozeik1, Dj Wheatley2, T Gourlay2

  • 1Department of Biomedical Engineering, University of Strathclyde, Glasgow, UK monica.rozeik@strath.ac.uk.

Perfusion
|February 27, 2014
PubMed

Insights

Transcatheter aortic valve replacement (TAVR) offers a vital treatment for aortic stenosis. Improving TAVR technology can overcome complications and enhance prosthesis durability for better patient outcomes.

Area of Science:

  • Cardiovascular Science
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • The aortic valve functions under significant hemodynamic stress, with over 100,000 daily cycles.
  • Aortic stenosis, a severe complication, has a poor prognosis without intervention, with surgical valve replacement as the current standard.
  • Understanding native aortic valve anatomy and function is crucial for developing effective prosthetic replacements.

Approach:

  • This review examines the anatomy, structure, and pathology of the aortic valve.
  • It discusses the implications of these factors for transcatheter aortic valve replacement (TAVR) device design.
  • The review highlights current TAVR complications and potential solutions.

Key Points:

  • Aortic valve disease necessitates advanced prosthetic solutions.
  • Transcatheter aortic valve replacement (TAVR) is a key therapeutic approach.
  • Reducing delivery profile and enhancing imaging are critical for TAVR success.

Conclusions:

  • Further advancements in TAVR technology are needed to address complications like bleeding, conduction disturbances, and patient-prosthesis mismatch.
  • Optimizing TAVR aims for a fully functional and durable aortic valve prosthesis.
  • Improved imaging and device design are essential for overcoming current TAVR limitations.

Keywords:
aortic valve diseaseaortic valve replacementheart valvestranscathetervalve structure

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