Related Experiment Video
Updated: May 2, 2026

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
Published on: March 21, 2025
The influence of prior practice and handedness on the orthogonal Simon effect
Cristina Iani1, Nadia Milanese1, Sandro Rubichi1
1Department of Communication and Economics, University of Modena and Reggio Emilia Reggio Emilia, Italy.
Abstract:
When stimuli are arranged vertically and responses horizontally, right-handed participants respond faster with right responses to stimuli presented above fixation and with left responses to stimuli presented below fixation, even when stimulus position is task-irrelevant (orthogonal Simon effect). The aim of the present work was twofold. First, we assessed whether the orthogonal Simon effect evident in right-handed participants is present also for left-handed participants (Experiment 1). Second, we investigated whether for both groups of participants the orthogonal Simon effect is influenced by the stimulus-response (S-R) mapping used for an orthogonal spatial S-R compatibility task performed 5 min before (Experiment 2). Our results showed that the orthogonal Simon effect significantly differed in the two groups, with left-handers showing an advantage for the up-left/down-right mapping (Experiment 1). Interestingly, the orthogonal Simon effect was strongly influenced by prior practice regardless of the participants' handedness (Experiment 2). These results suggest that the short-term S-R associations acquired during practice can override the long-term, hardwired associations established on the basis of handedness.
Related Concept Videos
Lateralization
Causes of Similarity-Dissimilarity Effect

