Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods for Studying Drug Absorption: In situ01:09

Methods for Studying Drug Absorption: In situ

887
In situ experiments, such as the Doluisio method and Single-Pass Perfusion technique, provide critical insights into drug uptake by simulating in vivo conditions for drug absorption.
The Doluisio method involves perfusing a prepared segment of a rat's small intestine with a solution of radiolabeled drug and a non-absorbable marker. This helps to differentiate between absorbed and non-absorbed drug concentrations. The intestinal segment is connected at both ends using tubing and syringes,...
887

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipidomic profile of meningiomas harboring different NF2 mutation status.

Metabolomics : Official journal of the Metabolomic Society·2026
Same author

Culture Dimensionality Modulates Gallium Maltolate Response in Glioblastoma: Comparative Analyses in 2D and 3D Models.

Molecular pharmaceutics·2026
Same author

Assessment of thermal and solvent stable SPME fibers for volatilome investigation through in vitro experiments with cancer cell lines.

Analytica chimica acta·2025
Same author

Profiling of Volatile Metabolites of <i>Escherichia coli</i> Using Gas Chromatography-Mass Spectrometry.

International journal of molecular sciences·2025
Same author

Pharmacological characterisation of psilocybin and 5-MeO-DMT discriminative cues in the rat and their translational value for identifying novel psychedelics.

Journal of psychopharmacology (Oxford, England)·2025
Same author

Minimally Invasive Chemical Biopsy Needle with Self-Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same journal

Incorporation of Engineered Cu<sup>0</sup>/Cu<sup>+</sup> Interfaces in Metal-Organic Frameworks for Boosting CO<sub>2</sub> Hydrogenation to Methanol.

Angewandte Chemie (International ed. in English)·2026
Same journal

Planar Chiral Carbazole-Naphthalene Bisimide Hetero-Cyclophane for Circularly Polarized Delayed Fluorescence.

Angewandte Chemie (International ed. in English)·2026
Same journal

Charge-Transfer Exciton Flows: Red Luminescent Zn<sub>8</sub>D<sub>14</sub>A<sub>4</sub> Nanotubes.

Angewandte Chemie (International ed. in English)·2026
Same journal

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity.

Angewandte Chemie (International ed. in English)·2026
Same journal

Suppressing Interfacial-Accelerated Degradation in Perovskite Solar Cells via Supramolecular Co-Assembly.

Angewandte Chemie (International ed. in English)·2026
Same journal

Isolation and Reactivity of a Stannabismuthene.

Angewandte Chemie (International ed. in English)·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

In Vivo Microdialysis Method to Collect Large Extracellular Proteins from Brain Interstitial Fluid with High-molecular Weight Cut-off Probes
08:17

In Vivo Microdialysis Method to Collect Large Extracellular Proteins from Brain Interstitial Fluid with High-molecular Weight Cut-off Probes

Published on: September 26, 2018

14.3K

Solid-phase microextraction: a complementary in vivo sampling method to microdialysis

Erasmus Cudjoe1, Barbara Bojko, Inés de Lannoy

  • 1Department of Chemistry, University of Waterloo, 200 University Avenue, Waterloo, N2L 3G1 (Canada) http://spme.uwaterloo.ca.

Angewandte Chemie (International Ed. in English)
|February 28, 2014
PubMed
Summary

No abstract available in PubMed .

Keywords:
analytical methodsin vivo samplingliquid chromatographymass spectrometrymetabolomics

More Related Videos

Dissolved Solute Sampling Across an Oxic-Anoxic Soil-Water Interface Using Microdialysis Profilers
11:43

Dissolved Solute Sampling Across an Oxic-Anoxic Soil-Water Interface Using Microdialysis Profilers

Published on: March 24, 2023

2.7K
Hippocampal Insulin Microinjection and In vivo Microdialysis During Spatial Memory Testing
10:32

Hippocampal Insulin Microinjection and In vivo Microdialysis During Spatial Memory Testing

Published on: January 11, 2013

16.1K

Related Experiment Videos

Last Updated: May 2, 2026

In Vivo Microdialysis Method to Collect Large Extracellular Proteins from Brain Interstitial Fluid with High-molecular Weight Cut-off Probes
08:17

In Vivo Microdialysis Method to Collect Large Extracellular Proteins from Brain Interstitial Fluid with High-molecular Weight Cut-off Probes

Published on: September 26, 2018

14.3K
Dissolved Solute Sampling Across an Oxic-Anoxic Soil-Water Interface Using Microdialysis Profilers
11:43

Dissolved Solute Sampling Across an Oxic-Anoxic Soil-Water Interface Using Microdialysis Profilers

Published on: March 24, 2023

2.7K
Hippocampal Insulin Microinjection and In vivo Microdialysis During Spatial Memory Testing
10:32

Hippocampal Insulin Microinjection and In vivo Microdialysis During Spatial Memory Testing

Published on: January 11, 2013

16.1K