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Updated: May 2, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Using population screening for recruitment of young adults engaged in illicit drug use: methodological issues and
Andrew Smirnov1, Robert Kemp2, Helene Wells3
1Queensland Alcohol and Drug Research and Education Centre, School of Population Health, The University of Queensland, Herston Rd, Herston, QLD 4006, Australia; Drug Harm Reduction Branch, Health Protection Directorate, Queensland Health, Division of the Chief Health Officer, Butterfield St, Herston, QLD 4006, Australia.
Abstract:
Social stigma, legal sanctions and the associated lack of sampling frames create barriers to the probabilistic sampling of those engaged in a variety of behaviour, including illicit drug use. We used a novel sampling approach to recruit respondents into a longitudinal study examining amphetamine-type stimulant use. A young adult population was screened for lifetime drug use to create a sampling frame of amphetamine-type stimulant users and non-users. We posted 12,118 screening questionnaires to a random selection of young adults listed on the electoral roll for Brisbane and the Gold Coast, Australia (N=107,275). Using a small pre-paid incentive and intensive telephone and postal reminders we attained a screening response rate of 49.9%. Eligible amphetamine-type stimulant users (used ecstasy or methamphetamine⩾3 times in past 12 months) and non-users (never used ecstasy or methamphetamine) were identified by screening responses. About two-thirds of each selected group took part in the longitudinal study. Comparisons with large-scale population survey data suggest the sample was broadly representative of young adult amphetamine-type stimulant users in Australia.
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