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Post-catheterisation arterial thrombosis in children--pathophysiology, prevention, and treatment

João Silva Marques1, Cristina Gonçalves2

  • 11Department of Cardiology I,Santa Maria Hospital - CHLN,Lisbon Academic Medical Centre,CCUL,Lisbon,Portugal.

Cardiology in the Young
|March 1, 2014
PubMed

Insights

Lower limb ischaemia, a frequent cardiac catheterisation complication in children, can cause disability. Further research is needed on optimal prevention and treatment strategies for arterial access site thrombosis.

Area of Science:

  • Pediatric Cardiology
  • Vascular Surgery
  • Interventional Radiology

Background:

  • Lower limb ischaemia is the most frequent complication of cardiac catheterisation in children.
  • This complication can lead to significant disability and limit future arterial access.
  • It is often overlooked, necessitating a focused review of management strategies.

Purpose of the Study:

  • To review the current literature on arterial access site thrombosis in children.
  • To focus on evidence supporting preventive and treatment strategies.
  • To identify gaps in knowledge regarding optimal diagnostic and therapeutic approaches.

Main Methods:

  • A narrative review of existing literature was performed.
  • The review focused on studies addressing arterial access site thrombosis in pediatric patients.
  • Evidence regarding anticoagulation, thrombolysis, and thrombectomy was specifically examined.

Main Results:

  • Anticoagulation, thrombolysis, and thrombectomy have been successfully employed in treating arterial access site thrombosis.
  • The optimal role and timing for each treatment modality remain incompletely established.
  • Current evidence highlights the need for further investigation into these interventions.

Conclusions:

  • Prospective investigation of diagnostic and therapeutic strategies is essential.
  • Clarifying the role of novel pharmacologic interventions is crucial.
  • Further research is required to define the optimal use of percutaneous and surgical thrombectomy in pediatric patients.

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