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Updated: Aug 19, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Evaluation of global and regional left ventricular function using two-dimensional and M-mode echocardiography in
H J Trappe1, W G Daniel, H Klein
1Department of Internal Medicine, University Hospital, Hannover, West Germany.
Abstract:
The effects of glued epicardial patch electrodes of the automatic implantable cardioverter defibrillator on the left ventricular function was studied by two-dimensional and M-mode echocardiography in 15 patients. Pre- and postoperative end-diastolic and end-systolic left ventricular cross-sectional areas were evaluated using planimetry. Regional left ventricular wall motion at the level of the left ventricular patch electrode was analyzed by two end-diastolic and end-systolic perpendicular axes. Left ventricular end-diastolic and end-systolic diameters as well as E-point-septal-separation and fractional shortening were analyzed using M-mode echocardiography. The mean time interval between preoperative echocardiograms and implantation of the automatic defibrillator was 0.3 X 1.3 (less than 1-2) months. Postoperative echocardiograms were recorded 6.6 +/- 6.9 (0.5-24) months after implantation of the device. There were no significant differences between pre- and postoperative mean values of end-diastolic and end-systolic areas and axes as well as M-mode echocardiographic parameters. Our data show that left ventricular patch electrodes do not significantly alter global or regional left ventricular function in patients after implantation of the automatic defibrillator.
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