[Histone modifications during spermatogenesis and male infertility]

Xiao-yan Pan1, Zhi-xin Li1, Zheng-chao Wang2

  • 1Department of Histology and Embryology, Jilin Medical College, Jilin, Jilin 132013, China.

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Histone Modification02:32

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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