Related Experiment Video
Updated: May 2, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Antibacterial, kinetics and bacteriolytic properties of silver(I) pyridinedicarboxylate compounds
M Ignacio Azócar1, Grace Gómez1, Carla Velásquez1
1Facultad de Química y Biología, Universidad de Santiago de Chile, Av. Bernardo O'Higgins 3363, Santiago, Chile.
Abstract:
Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) were studied against Escherichia coli, Listeria monocytogenes (ISP-65-08), Salmonella typhi and Staphylococcus aureus (ATCC 25923) using kinetics of grown inhibition, viability assays, minimum inhibitory concentration and optical microscopy. The 3 silver compounds were tested toward UV-radiation in order to characterize their light insensitivity for potential medical devices: UV-radiation curable polymers. Photophysical measurements show remarkable differences toward UV-radiation, which were explained based on their polymeric structures with multiple nature bonds between pyridinedicarboxylic ligands and Ag(I) centers. We found a bacteriolytic effect and differences in the antibacterial efficiency depending on the structure of the complexes and the nature of AgX (X=oxygen and nitrogen) bonds: AgQuinol>AgLutidin>AgIsocinchom.
More Related Videos
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
08:08Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Related Concept Videos
Antimicrobial Effectiveness
Inhibitors of Bacterial DNA Synthesis
Formation of Complex Ions
Inhibitors of Bacterial Protein Synthesis
Chemical Agents for Microbial Control