Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.4K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.4K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

2.2K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.2K
Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

28
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of...
28
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

28
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
28
Neural Regulation01:37

Neural Regulation

34.8K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
34.8K
Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

29
Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
29

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding the Aggregation Mechanism of and Developing Stabilization Strategies for Recombinant Fibroblast Growth Factor 2.

Biomolecules·2026
Same author

Overcoming the diagnostic gap in mild cognitive impairment in Parkinson's disease: a pilot study employing a machine learning-/augmented reality-based digital biomarker.

Frontiers in aging neuroscience·2026
Same author

A case-control study examining the relationship between social cognition and post-traumatic stress disorder.

BJPsych open·2026
Same author

Measles Seroprevalence Among Healthcare Workers in a Tertiary Hospital in Central Greece, 2017.

Vaccines·2026
Same author

The Charcot shower.

Arquivos de neuro-psiquiatria·2026
Same author

Corrigendum to "Fornix subdivisions and spatial learning: a diffusion MRI study" [Neuropsychologia 222, 15 February 2026, 109350].

Neuropsychologia·2026

Related Experiment Video

Updated: May 2, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.7K

Problematic Internet use in Parkinson's disease.

Kit Wu1, Marios Politis2, Sean S O'Sullivan3

  • 1Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London, London W12 0NN, UK.

Parkinsonism & Related Disorders
|March 4, 2014
PubMed
Summary
This summary is machine-generated.

Parkinson's disease patients with impulse control disorders (ICDs) show increased problematic Internet use (PIU) compared to those without ICDs and healthy individuals. Clinicians should screen for excessive Internet use in this patient group.

Keywords:
Computer useImpulse control disorderInternet addictionParkinson's diseaseProblematic Internet useYale-Brown Obsessive Compulsive Scale

More Related Videos

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.4K
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

25.1K

Related Experiment Videos

Last Updated: May 2, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.7K
Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.4K
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

25.1K

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Clinical Psychology

Background:

  • Problematic Internet use (PIU) is linked to impulse control disorders (ICDs) and shares behavioral addiction traits.
  • Internet use has not been systematically studied in Parkinson's disease (PD) patients.
  • PD is a neurodegenerative disorder affecting motor control and potentially influencing behavioral patterns.

Purpose of the Study:

  • To investigate Internet use patterns in Parkinson's disease patients with and without ICDs.
  • To compare Internet usage between PD patients with ICDs, PD patients without ICDs, and healthy controls.
  • To determine if PD patients with ICDs exhibit greater problematic Internet use, particularly related to their specific disorders.

Main Methods:

  • A cross-sectional study involving 29 PD patients with ICDs, 20 PD patients without ICDs, and 19 healthy controls.
  • All participants confirmed non-essential Internet use.
  • Semi-structured interviews and the Yale-Brown Obsessive Compulsive Scale adapted for Internet use (Y-BOCS-Internet) were administered.

Main Results:

  • PD patients with ICDs scored significantly higher on the Y-BOCS-Internet compared to PD patients without ICDs and healthy controls (13.69 vs. 5.42 vs. 4.70).
  • The PD-ICD group reported increased time spent on the Internet, greater difficulty resisting use, more intrusive thoughts about the Internet, and higher life interference due to Internet use.
  • Statistical analysis revealed significant differences across groups for these measures (p < 0.0001 for most).

Conclusions:

  • Parkinson's disease patients with ICDs demonstrate a heightened propensity for excessive Internet use.
  • This excessive Internet use is characterized by compulsive engagement and significant life disruption.
  • Healthcare providers should proactively assess for problematic Internet use in PD patients diagnosed with ICDs.