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Multiple ischemic strokes caused by nonbacterial thrombotic endocarditis because of gallbladder cancer: a case report
Akiko Yamane1, Hirokazu Sadahiro1, Hisaharu Goto1
1Department of Neurosurgery, Yamaguchi University Hospital, Yamaguchi, Japan.
Abstract:
We report a case of a 62-year-old woman with multiple ischemic strokes caused by nonbacterial thrombotic endocarditis (NBTE) because of gallbladder cancer. Transesophageal echocardiography showed NBTE on the mitral valve. The NBTE disappeared with anticoagulation treatment for 2 weeks. Abdominal computed tomography showed a gallbladder tumor that was surgically resected. Histopathologic studies showed poorly differentiated tumor cells and the production of mucin. Trousseau syndrome with gallbladder cancer is very rare. We suggest that the development of NBTE is related to the production of mucin.
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