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Updated: May 2, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma
Saba Al-Bazzaz1, Jason Karamchandani, Eva Mocarski
1Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, 30 Bond Street, Toronto, ON, Canada, M5B 1W8, albazzazs@smh.ca.
Abstract:
We report the presence of pituitary tissue in a benign ovarian cystic teratoma removed surgically from a 43-year-old woman. The pituitary consisted of non-tumorous neurohypophysis and adenohypophysis containing mainly prolactin (PRL)-immunopositive cells (80 % of cells) and a small PRL-producing adenoma. The ultrastructure of the tumor cells differed significantly from PRL cells in the non-tumorous and adenomatous intrasellar pituitary. It appears that cells differing in ultrastructure from intrasellar pituitary PRL cells can also produce PRL.
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