Related Experiment Video
Updated: May 2, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
Published on: March 8, 2015
Rescue GPi-DBS for a Stroke-associated Hemiballism in a Patient with STN-DBS
Genko Oyama1, Nicholas Maling1, Amanda Avila-Thompson1
1Departments of Neurology and Neurosurgery, Center for Movement Disorders & Neurorestoration, University of Florida, Gainesville, Florida, United States of America.
Background:
Hemiballism/hemichorea commonly occurs as a result of a lesion in the subthalamic region.
Case Report:
A 38-year-old male with Parkinson's disease developed intractable hemiballism in his left extremities due to a small lesion that was located adjacent to the right deep brain stimulation (DBS) lead, 10 months after bilateral subthalamic nucleus (STN)-DBS placement. He underwent a right globus pallidus internus (GPi)-DBS lead implantation. GPi-DBS satisfactorily addressed his hemiballism.
Discussion:
This case offered a unique look at basal ganglia physiology in human hemiballism. GPi-DBS is a reasonable therapeutic option for the treatment of medication refractory hemiballism in the setting of Parkinson's disease.

