Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building
1Technical Institute of Physics and Chemistry, CAS, Beijing 100190, China. niu@mail.ipc.ac.cn.
Abstract:
A method for site-specific and high yield modification of tobacco mosaic virus coat protein (TMVCP) utilizing a genetic code expanding technology and copper free cycloaddition reaction has been established, and biotin-functionalized virus-like particles were built by the self-assembly of the protein monomers.


