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Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

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In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
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Van de Graaff generators (or Van de Graaffs) are devices used to demonstrate high voltage due to static electricity that can also be used for research. Robert Van de Graaff first built one in 1931 (based on original suggestions by Lord Kelvin) for use in nuclear physics research.
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The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
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Inductively coupled plasma (ICP) is the most widely used plasma source in atomic emission spectroscopy (AES), also known as Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The ICP source, or torch, consists of three concentric quartz tubes with argon gas flowing through them. A spark from a Tesla coil initiates the ionization of argon, generating a high-temperature plasma.
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Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
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Related Experiment Video

Updated: May 2, 2026

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
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Development of a high current H(-) ion source for cyclotrons.

H Etoh1, Y Aoki1, H Mitsubori1

  • 1Technology Research Center, Sumitomo Heavy Industries, Ltd., Yokosuka, Japan.

The Review of Scientific Instruments
|March 6, 2014
PubMed
Summary

A new multi-cusp DC H(-) ion source for medical cyclotrons achieved 16 mA of negative ion beam current. This was accomplished using cesium seeding and optimizing the source design for efficient operation.

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Area of Science:

  • Nuclear Physics
  • Plasma Physics
  • Medical Physics

Background:

  • Cyclotrons are essential for medical isotope production and particle therapy.
  • High-intensity negative hydrogen ion (H(-)) beams are crucial for efficient cyclotron operation.
  • Existing ion sources require optimization for enhanced beam current and stability.

Purpose of the Study:

  • To design and fabricate a multi-cusp DC H(-) ion source for medical cyclotron applications.
  • To optimize key operational parameters for improved negative ion beam current.
  • To evaluate the effect of cesium seeding on ion source performance.

Main Methods:

  • Designed and fabricated a multi-cusp DC H(-) ion source.
  • Optimized filament configuration, magnetic filter strength, and extraction electrode geometry.
  • Introduced a small quantity of cesium (Cs) into the ion source.

Main Results:

  • Achieved a stable DC H(-) ion beam current of 16 mA.
  • Demonstrated enhanced beam current with cesium-seeded operation.
  • Operated the ion source at a low arc discharge power of 2.8 kW.

Conclusions:

  • The developed multi-cusp DC H(-) ion source is suitable for medical cyclotron applications.
  • Cesium seeding significantly enhances negative ion beam current.
  • The optimized source design offers efficient performance at low power consumption.