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Nanomedicine-based strategies for treatment of atherosclerosis

Maximilian Schiener1, Martin Hossann2, Joana R Viola3

  • 1Institute for Cardiovascular Prevention (IPEK), LMU Munich, 80336 Munich, Germany; Department of Radiation Oncology, LMU Munich, 81377 Munich, Germany.

Trends in Molecular Medicine
|March 6, 2014
PubMed

Insights

Nanomedicine offers promising strategies for treating atherosclerosis, a chronic inflammatory arterial disease. Current nanomedical formulations can target arterial wall inflammation, advancing personalized medicine approaches.

Area of Science:

  • Cardiovascular Research
  • Nanomedicine
  • Inflammatory Diseases

Background:

  • Atherosclerosis is a chronic inflammatory arterial disease driven by lipid metabolism imbalance and inflammation.
  • Despite extensive research, clinical translation of atherosclerosis mechanisms remains limited.
  • Nanomedicine shows potential for atherosclerosis treatment, drawing parallels with antitumor therapy advancements.

Purpose of the Study:

  • To review current nanomedical formulations for atherosclerosis treatment.
  • To explain how these formulations target arterial wall inflammation.
  • To discuss the potential of nanomedicine in personalized atherosclerosis therapy.

Main Methods:

  • Review of existing nanomedical formulations optimized for atherosclerosis.
  • Analysis of strategies for targeting inflammatory processes in the arterial wall using nanomedicine.
  • Evaluation of the potential and limitations of nanomedical applications.

Main Results:

  • Nanomedical formulations are being developed to target atherosclerosis.
  • These formulations can be engineered to target inflammatory pathways in the arterial wall.
  • Current nanomedical approaches show promise for personalized medicine.

Conclusions:

  • Nanomedicine presents a promising avenue for atherosclerosis treatment.
  • Targeting arterial wall inflammation with nanomedicine is a key strategy.
  • Further research is needed to enhance atherosclerosis-specific targeting for improved clinical outcomes.
Keywords:
atherosclerosisinflammationliposomenanomedicine

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