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Mango peel pectin as a carrier for solid dispersions
Shobhit Kumar1, Satish Kumar Gupta1
1Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India.
Objectives:
The present study describes the evaluation of pectin as a carrier for solid dispersion.
Material And Methods:
Pectin was extracted from mango peel. Solid dispersions were prepared by using pectin to enhance the dissolution rate of the drug. Aceclofenac was used as the model drug.
Results:
Solid dispersion containing pectin had comparatively less release of the drug as compared to lactose for a particular time period.
Conclusions:
The slower release may be due to the solubility of pectin in an aqueous fluid and it's swelling capacity. With that in mind, it can be used as a carrier to prepare solid dispersions.
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