Primary leiomyosarcoma of the penis: a case report
Lawrence D'Cruze1, A Boobala2, Subalakshmi Balasubramanian3
1Assistant Professor, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai - 600116, India .
Journal of Clinical and Diagnostic Research : JCDR
|March 6, 2014
Summary
Primary penile leiomyosarcoma is an extremely rare cancer. This report details a case of a 59-year-old man diagnosed with high-grade leiomyosarcoma of the penis, confirmed via immunohistochemistry.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Primary leiomyosarcoma of the penis is exceptionally rare, with fewer than 50 cases documented in English literature.
- Penile sarcomas are often misdiagnosed due to their rarity and varied presentations.
Purpose of the Study:
- To report a rare case of primary penile leiomyosarcoma.
- To highlight diagnostic challenges and confirmative histopathological findings.
Main Methods:
- Clinical presentation of an ulceroproliferative penile lesion in a 59-year-old male.
- Histopathological examination of the tumor.
- Immunohistochemistry to confirm the diagnosis of leiomyosarcoma.
Main Results:
- The patient presented with a penile ulceroproliferative growth.
- Histopathology revealed a high-grade spindle cell sarcoma.
- Immunohistochemistry confirmed the tumor as leiomyosarcoma.
Conclusions:
- This case adds to the limited literature on primary penile leiomyosarcoma.
- Accurate diagnosis relies on thorough histopathological and immunohistochemical analysis.


