Atypical spindle cell lesions of the prostate

This report is a review of the spectrum of prostatic spindle cell lesions that are usually benign, but have morphologic features suggestive of high-grade malignancy. The problem is complicated further by the extreme rarity and heterogeneity of such lesions. Sixteen cases of atypical prostatic spindle cell proliferations are reported, and the differential diagnosis with malignancy is reviewed.