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Dengue fever presenting with acute cerebellitis: a case report
Milinda Withana, Chaturaka Rodrigo1, Thashi Chang
1Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. chaturaka.rodrigo@gmail.com.
BMC Research Notes
|March 7, 2014
Summary
Dengue fever can cause rare neurological issues. This case highlights acute cerebellitis, a cerebellar syndrome, as the initial symptom of dengue infection in a Sri Lankan woman.
Area of Science:
- Neurology
- Infectious Diseases
- Tropical Medicine
Background:
- Dengue fever incidence is increasing globally, particularly in tropical regions.
- Rare neurological manifestations of dengue are increasingly recognized.
- Sri Lanka reported nearly 45,000 dengue cases in 2012.
Observation:
- A 45-year-old woman presented with acute febrile illness and significant gait unsteadiness.
- Clinical examination revealed cerebellar signs including dysarthria, nystagmus, dysmetria, dysdiadokokinesia, and ataxia.
- Diagnostic tests confirmed acute dengue infection (NS1 antigen and IgM positive).
Findings:
- The patient experienced acute cerebellitis as the presenting feature of dengue infection.
- Cerebellar symptoms persisted for a week after fever resolution.
- Brain MRI was normal, and cerebellar signs resolved spontaneously within 17 days.
Implications:
- This is the first reported case of dengue presenting primarily with cerebellitis.
- Highlights the diverse and unusual neurological spectrum of dengue virus infection.
- Emphasizes the need for considering dengue in febrile patients with neurological symptoms, especially in endemic areas.
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