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Preanalytical quality in clinical chemistry laboratory
M Imteyaz Ahmad1, K L Ramesh2, Ravi Kumar3
1Department of Biochemistry, PGIMER & Dr Ram Manohar Lohia Hospital, New Delhi, India. dr.imteyaz579@gmail.com
Clinical Laboratory
|March 8, 2014
Summary
Haemolysis prevalence in blood samples varied significantly between outpatient and inpatient departments, indicating differences in preanalytical quality. The haemolysis index (HI) is a valuable tool for monitoring this quality.
Area of Science:
- Clinical Chemistry
- Laboratory Medicine
- Quality Assurance
Background:
- Haemolysis in blood samples often results from poor specimen collection or handling.
- Haemolysis is a potential indicator of preanalytical quality in laboratory testing.
Purpose of the Study:
- To investigate the prevalence of haemolysis in routine venous blood samples.
- To identify differences in preanalytical quality between outpatient departments (OPDs) and inpatient departments (IPDs).
Main Methods:
- Haemolysis index (HI) values were analyzed for samples from OPDs and IPDs.
- Haemolysis was defined as a HI greater than or equal to 15.
Main Results:
- Samples from OPDs showed a higher prevalence of haemolysis compared to the lowest prevalence center.
- 10.4% of samples from primary healthcare were haemolysed versus 31.1% from IPDs (p=0.001).
- Significant differences in haemolysis rates were observed between IPD sections (34.8% vs. 11.3%, p=0.001).
Conclusions:
- Variations in haemolysis indices suggest differing preanalytical conditions across healthcare units.
- The haemolysis index (HI) is a useful tool for assessing and tracking preanalytical quality in clinical laboratories.
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