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A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
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Maternal genital tract colonisation by group-B streptococcus: a hospital based study
Nida Najmi1, Imtiaz Jehan2, Rozina Sikandar3
1Department of Obstetrics & Gynecology, The Aga Khan University Hospital, Karachi. nida.najmi@aku.edu
JPMA. the Journal of the Pakistan Medical Association
|March 8, 2014
Summary
Group B Streptococcus (GBS) colonisation affects 17% of pregnant women. Lower body mass index was a risk factor, suggesting GBS screening is vital during antenatal care for all expectant mothers.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Microbiology
Background:
- Group B Streptococcus (GBS) is a common bacterium that can cause serious infections in newborns.
- Genital tract colonization by GBS in pregnant women is a significant public health concern.
- Understanding the prevalence and risk factors of GBS colonization is crucial for effective prevention strategies.
Purpose of the Study:
- To determine the prevalence of Group B Streptococcus (GBS) genital tract infection in pregnant women.
- To identify risk factors associated with GBS colonization in this population.
Main Methods:
- A cross-sectional study was conducted at two hospitals in Karachi, Pakistan.
- 405 pregnant women at 35-37 weeks gestation were recruited using stratified sampling.
- High vaginal swabs were analyzed, and logistic regression was used to assess risk factors.
Main Results:
- The overall prevalence of GBS colonization was 17%.
- Prevalence varied between hospitals (22.6% at Aga Khan Hospital vs. 13.6% at Sobhraj Hospital).
- Lower body mass index was significantly associated with GBS colonization (OR 0.91).
Conclusions:
- Group B Streptococcus screening should be integrated into routine antenatal care.
- Universal screening for GBS in pregnant women is recommended.
- Early detection and management can reduce the risk of GBS-related complications.
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