Related Experiment Video
Updated: May 2, 2026

08:02
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
5.3K
Allergic contact dermatitis to a laptop computer in a child
Sharon E Jacob1, Shehla Admani
1Division of Dermatology, University of California, San Diego, Rady Children's Hospital, San Diego, California.
Pediatric Dermatology
|March 8, 2014
Summary
An 11-year-old boy developed widespread dermatitis from nickel in a new laptop. This case highlights allergic contact dermatitis from electronic devices.
Area of Science:
- Dermatology
- Allergology
- Environmental Health
Background:
- Atopic dermatitis is a common chronic inflammatory skin condition.
- Electronic devices are increasingly prevalent in daily life.
- Nickel allergy is a frequent cause of allergic contact dermatitis.
Observation:
- An 11-year-old boy with a history of atopic dermatitis presented with a widespread rash.
- The dermatitis appeared one month after receiving a new laptop.
- The rash distribution suggested contact with the laptop.
Findings:
- Patch testing confirmed allergic contact dermatitis to nickel.
- The nickel was identified as originating from the laptop casing.
- This represents a case of device-related allergic contact dermatitis.
Implications:
- Nickel in consumer electronics can cause allergic contact dermatitis.
- Awareness is needed regarding potential allergens in electronic devices.
- Further investigation into material composition of electronics may be warranted.
Related Concept Videos
Drug Toxicity: Allergic Reactions
209
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
209
Allergic Reactions: Anaphylaxis
280
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
280
Allergic Drug Reactions
1.6K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.6K
Allergic Reactions
26.4K
Overview
26.4K
Hypersensitivities
7.3K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
7.3K
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K

