Related Experiment Video
Updated: May 2, 2026

A Delayed Inoculation Model of Chronic Pseudomonas aeruginosa Wound Infection
Published on: February 20, 2020
Acute and chronic paronychia of the hand
Abstract:
Acute and chronic infections and inflammation adjacent to the fingernail, or paronychia, are common. Paronychia typically develops following a breakdown in the barrier between the nail plate and the adjacent nail fold and is often caused by bacterial or fungal pathogens; however, noninfectious etiologies, such as chemical irritants, excessive moisture, systemic conditions, and medications, can cause nail changes. Abscesses associated with acute infections may spontaneously decompress or may require drainage and local wound care along with a short course of appropriate antibiotics. Chronic infections have a multifactorial etiology and can lead to nail changes, including thickening, ridging, and discoloration. Large, prospective studies are needed to identify the best treatment regimen for acute and chronic paronychia.
Insights
Paronychia, an infection around the fingernail, has common acute and chronic forms. Treatment for acute cases involves drainage and antibiotics, while chronic paronychia has varied causes and nail changes.
Area of Science:
- Dermatology
- Infectious Diseases
Background:
- Paronychia involves infections and inflammation adjacent to the fingernail.
- It commonly arises from a compromised barrier between the nail plate and nail fold.
- Causes include bacterial, fungal, and noninfectious factors like irritants or systemic conditions.
Purpose of the Study:
- To review the common causes, presentations, and management of acute and chronic paronychia.
- To highlight the need for further research into optimal treatment strategies.
Main Methods:
- Literature review of paronychia etiology, pathogenesis, and treatment.
- Analysis of clinical presentations of acute and chronic paronychia.
- Discussion of current therapeutic approaches.
Main Results:
- Acute paronychia may present with abscesses requiring drainage and antibiotics.
- Chronic paronychia has multifactorial origins and can result in significant nail deformities.
- Noninfectious causes, including irritants and medications, contribute to nail changes.
Conclusions:
- Effective management of acute paronychia includes wound care and antibiotics.
- Chronic paronychia treatment is complex due to its varied etiology and potential for nail damage.
- Further large-scale prospective studies are essential to establish evidence-based treatment guidelines.
Related Concept Videos
Hand hygiene
Hand washing...
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis II: Pathophysiology