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Chemiluminescence sensing of fluoride ions using a self-immolative amplifier
Ilke Simsek Turan1, Engin U Akkaya
1UNAM-National Nanotechnology Research Center and ‡Department of Chemistry, Bilkent University , Ankara 06800, Turkey.
Abstract:
An enhanced chemiluminescence signal is obtained when electronically triggered dioxetane cleavage is initiated by fluoride-mediated deprotection of the silyl-protecting group, followed by self-immolation via 1,4-quinone-methide rearrangement. The reaction takes place even when the probe is trapped within a PMMA layer on top of a glass plate. In that arrangement, fluoride in aqueous solutions can be detected selectively at low micromolar concentrations.
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