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Related Concept Videos

Larynx01:21

Larynx

6.4K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
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Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Advancements in the Fabrication of Synthetic Vocal Fold Models for Phonetic and Robotic Applications
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Author Spotlight: Advancements in the Fabrication of Synthetic Vocal Fold Models for Phonetic and Robotic Applications

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Subject-specific computational modeling of human phonation.

Qian Xue1, Xudong Zheng1, Rajat Mittal2

  • 1Department of Mechanical Engineering, University of Maine, Orono, Maine, 04469.

The Journal of the Acoustical Society of America
|March 11, 2014
PubMed
Summary

Direct numerical simulation of a subject-specific larynx model reveals realistic vocal fold dynamics and glottal flow during human phonation. Asymmetric laryngeal geometry significantly impacts vibration and flow, offering insights beyond simplified models.

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Area of Science:

  • Biomechanics
  • Fluid Dynamics
  • Acoustic Science

Background:

  • Human phonation is a complex biomechanical process involving airflow and vocal fold vibration.
  • Previous models often simplify laryngeal geometry, potentially limiting the accuracy of simulation results.
  • Understanding subject-specific laryngeal dynamics is crucial for diagnosing and treating voice disorders.

Purpose of the Study:

  • To conduct a direct numerical simulation of flow-structure interaction in a subject-specific larynx model.
  • To investigate human phonation under physiological conditions using realistic geometry.
  • To examine the effects of asymmetric laryngeal configuration on vocal fold dynamics and glottal flow.

Main Methods:

  • Direct numerical simulation (DNS) of fluid-structure interaction (FSI).
  • Utilized a subject-specific larynx model with realistic geometry.
  • Compared simulation results with established human phonation data.

Main Results:

  • Simulation outcomes align well with existing human data.
  • Generated glottal flow and waveform fall within normal physiological ranges.
  • Demonstrated that asymmetric anterior-posterior laryngeal geometry induces significant asymmetries in vocal fold vibration and glottal flow, unobserved in simplified models.

Conclusions:

  • Subject-specific numerical simulations provide valuable insights into human phonation.
  • Realistic laryngeal geometry is critical for accurately capturing vocal fold dynamics and glottal flow patterns.
  • The study highlights the limitations of simplified models in representing complex phonation phenomena.