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Combination chemotherapy with carboplatin and bleomycin for advanced and recurrent head and neck cancer: a phase II
J L Gonzalez-Vela1, L Panasci, M Black
1Oncology Department, Jewish General Hospital, Montreal, Quebec, Canada.
Journal of Surgical Oncology
|November 1, 1988
Abstract:
Carboplatin is a platinum analogue with activity reported in head and neck cancer. We conducted a phase II trial with 14 patients who had recurrent head and neck cancer. They were treated with carboplatin 300 mg/m2 intravenously (I.V.) and bleomycin 30 units I.V. every 4 weeks. No responses were observed in this group of patients. Dose intensity of carboplatin administration may be an important determinant of response.