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Updated: May 2, 2026
14:54
Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
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Optic neuropathy caused by Propionibacterium acnes pachymeningitis
Ore-Ofe O Adesina1, Brian C Stagg, Kathleen B Digre
1Departments of Ophthalmology (O-OOA, BCS, KBD, BJK, JEAW), Radiology (EPQ), Pathology (CAP), and Neurology (KBD, BJK, JEAW), University of Utah, Salt Lake City, Utah.
Summary
Propionibacterium acnes pachymeningitis caused vision loss in a patient. Prompt antibiotic treatment stabilized the optic neuropathy, preserving vision.
Area of Science:
- Neuro-ophthalmology
- Infectious Diseases
Background:
- Pachymeningitis, inflammation of the dura mater, can present with diverse neurological symptoms.
- Optic neuropathy, damage to the optic nerve, can lead to significant vision loss.
Observation:
- A case of vision loss attributed to optic neuropathy secondary to Propionibacterium acnes pachymeningitis is presented.
Findings:
- Propionibacterium acnes was identified as the causative agent of pachymeningitis.
- The patient's optic neuropathy demonstrated stabilization following targeted antibiotic therapy.
Implications:
- This case highlights the importance of considering infectious etiologies, such as Propionibacterium acnes, in cases of unexplained optic neuropathy.
- Effective management of underlying infections can lead to favorable outcomes in neuro-ophthalmic conditions.
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