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Published on: September 5, 2017
Latent and active tuberculosis: evaluation of injecting drug users
Mojgan Mamani1, Mohammad Mahdi Majzoobi1, Saadat Torabian2
1Department of Infectious Diseases, Hamedan University of Medical Sciences, Hamedan, IR Iran.
Background:
There is a high risk of tuberculosis (TB) infection among injecting drug users (IDUs).
Objectives:
This study aimed to determine the frequency of latent and active TB infection among IDUs.
Materials And Methods:
In a cross-sectional study between 2008 and 2009, IDUs referred to the methadone maintenance treatment (MMT) centers in Hamedan-Iran, undergone tuberculin skin test (PPD; purified protein derivative) were recruited. The participants with positive results for PPD test (> 5 mm and > 10 mm in HIV positive and negative cases), undergone other complementary procedures such as chest-X-ray and sputum smear test.
Results:
Overall, 268 IDUs between 18 and 70 (mean: 34.5 [8.2]) years were included in the study. PPD test had positive findings in 49 cases (18.3%). There was no significant difference of PPD positivity between HIV positive and negative participants (17.7% vs. 18.5%). An active TB was found among IDUs.
Conclusions:
The high prevalence of latent and active TB among IDUs indicates the need for TB screening tests among this population.
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