Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

35
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
35
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.6K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
Metastasis02:30

Metastasis

5.4K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.4K
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

33
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
33
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

755
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
755
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

900
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
900

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Palmoplantar keratoderma unveiling renal cell carcinoma: A novel paraneoplastic presentation.

Indian journal of dermatology, venereology and leprology·2016
Same author

Tuberculosis verrucosa cutis lesions exhibit a greater microvessel count than lupus vulgaris lesions.

Experimental dermatology·2016
Same author

Punctate Porokeratosis Palmaris et Plantaris.

Indian journal of dermatology·2015
Same author

Aggressive angiomyxoma.

Indian dermatology online journal·2014
Same author

Lichen Sclerosus Atrophicus [LSA] in the Areolae: A Case Report.

Case reports in dermatological medicine·2012
Same author

In-transit metastases from squamous cell carcinoma penis.

Indian journal of dermatology·2012
Same journal

Paraquat Tongue: A Poor Prognostic Marker.

Indian dermatology online journal·2026
Same journal

Comment on the Previously Published Article "Rare Masqueraders of Pure Neuritic Leprosy: A Report of Four Cases".

Indian dermatology online journal·2026
Same journal

Clinical and Dermoscopic Correlation in Secondary Syphilis: A Report of Three Cases.

Indian dermatology online journal·2026
Same journal

Dermoscopic Markers of Activity in Subtypes of Cutaneous Lupus Erythematosus in Skin of Color: An Observational Study.

Indian dermatology online journal·2026
Same journal

Evaluation of Melanocytes and T-cells in Vitiliginous Skin Pre- and Post-Narrow-Band UVB Phototherapy.

Indian dermatology online journal·2026
Same journal

Unusual Causes of Food-Induced Anaphylaxis - A Review.

Indian dermatology online journal·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
11:43

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

Published on: November 30, 2016

12.6K

Metastatic Crohn's disease.

Padmavathy Lanka1, Lakshmana Rao Lanka2, N Sylvester2

  • 1Division of Community Medicine, Urban Health Centre, Tamil Nadu, India.

Indian Dermatology Online Journal
|March 12, 2014
PubMed
Summary
This summary is machine-generated.

This report details a rare case of cutaneous Crohn's disease (CCD), also known as metastatic Crohn's disease (MSD), presenting without any gastrointestinal symptoms.

Keywords:
Cutaneous crohn's diseasemetastatic crohn's diseasenon caseating granulomas

More Related Videos

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

9.5K
Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection
07:42

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection

Published on: January 16, 2026

325

Related Experiment Videos

Last Updated: May 2, 2026

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
11:43

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

Published on: November 30, 2016

12.6K
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

9.5K
Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection
07:42

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection

Published on: January 16, 2026

325

Area of Science:

  • Gastroenterology and Dermatology
  • Inflammatory Bowel Disease Research

Background:

  • Crohn's disease is an inflammatory bowel disease known for intestinal and cutaneous manifestations.
  • Cutaneous Crohn's disease (CCD) is often synonymous with metastatic Crohn's disease (MSD).

Observation:

  • A rare case of CCD/MSD is presented.
  • This specific case exhibited no concurrent gastrointestinal involvement.

Findings:

  • The study highlights a unique presentation of CCD/MSD.
  • The absence of gastrointestinal symptoms in this case underscores the diverse clinical spectrum of the disease.

Implications:

  • This case expands the understanding of CCD/MSD presentations.
  • It emphasizes the importance of considering cutaneous manifestations even without apparent GI disease.