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Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor
Hsiangkuo Yuan1, Christy M Wilson, Jun Xia
1Department of Biomedical Engineering, Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA. tuan.vodinh@duke.edu.
Nanoscale
|March 13, 2014
Abstract:
Plasmonics-active gold nanostars exhibiting strong imaging contrast and efficient photothermal transduction were synthesized for a novel pulsed laser-modulated plasmonics-enhanced brain tumor microvascular permeabilization. We demonstrate a selective, optically modulated delivery of nanoprobes into the tumor parenchyma with minimal off-target distribution.
