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Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
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Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens

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Pseudomyxoma peritonei: a clinical case of this poorly understood condition

Ana Maria de Oliveira1, Catarina Graça Rodrigues1, Alexys Borges2

  • 1Department of Gastroenterology, Prof. Doutor Fernando Fonseca Hospital, Amadora, Portugal.

International Journal of General Medicine
|March 14, 2014
PubMed
Abstract

Insights

Pseudomyxoma peritonei, a rare mucinous tumor condition, can recur even after surgery. This case highlights the importance of monitoring patients for late-onset ascites and abdominal fullness.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Pseudomyxoma peritonei is a rare condition characterized by mucinous tumor deposits in the peritoneum, often originating from the appendix or ovary.
  • Its incidence is estimated at one to two per million worldwide annually.

Observation:

  • A 76-year-old woman presented with abdominal distension and dyspnea, diagnosed with pseudomyxoma peritonei.
  • She underwent surgical debulking, oophorectomy, and omentectomy, with histology confirming a colorectal/appendicular origin.

Findings:

  • The patient experienced disease recurrence 2 years and 8 months post-surgery, presenting with postprandial fullness and moderate ascites.
  • Chemotherapy was not administered due to her functional status.

Implications:

  • This case underscores the potential for late recurrence of pseudomyxoma peritonei.
  • It emphasizes the need for long-term surveillance in patients treated for this condition, even after successful debulking.
Keywords:
mucinous tumorpseudomyxoma debulkingpseudomyxoma peritonei

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