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Role of advanced glycation end products in cellular signaling

Christiane Ott1, Kathleen Jacobs2, Elisa Haucke3

  • 1Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, 07743 Jena, Germany.

Redox Biology
|March 14, 2014
PubMed

Keywords:
ADAMST, a disintegrin and metalloproteinase with a thrombospondin type 1 motifAGE, advanced glycation end productsAGE-receptorsAdvanced glycation end productsAge-associated diseasesAggregatesAgingE, from embryonic dayEGFR, epidermal growth factor receptorERK, extracellular-signal regulated kinaseF3NK, fructosamine 3-phosphokinaseFKHRL1, forkhead transcription factorHDL, high density lipoproteinHMGB1, high-mobility-group-protein B1HNE, 4-hydroxy-trans-2-nonenalJak1/2, Janus kinase 1/2LDL, low density lipoproteinMDA, malondialdehydeMEKK, mitogen-activated protein/ERK kinase kinasesMnSOD, manganese superoxide dismutaseNF-κBNf-κB, nuclear factor-light-chain-enhancer of activated BOxidative stressPIK3, phosphoinositol 3 kinaseRAGERAGE, receptor of AGEsRCC, reactive carbonyl compoundsReactive carbonyl compoundsS100B, S100 calcium binding protein BSIRt1, NAD+-dependent deacetylase and survival factor 1SR-A, scavenger receptor class ASignalingStat 1/2, signal transducers and activators of transcription 1/2VSMC, vascular smooth muscle cells

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