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Intravitreal thrombin activity is elevated in retinal vein occlusion

Thomas Bertelmann1, Thomas Stief, Walter Sekundo

  • 1aDepartment of Ophthalmology, Philipps-University bDepartment of Laboratory Medicine, Philipps-University, Marburg, Germany cDepartment of Ophthalmology, Feldkirch Regional Hospital, Feldkirch, Austria dDepartment of Ophthalmology, Goethe University, Frankfurt/Main, Germany eDoheny Eye Institute, Los Angeles, California, USA.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|March 15, 2014
PubMed
Summary

Intravitreal thrombin activity is elevated in eyes with branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) compared to healthy controls. This finding suggests thrombin may be a new marker for blood-retina barrier breakdown in retinal vein occlusions.

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