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Updated: May 2, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Good two-year outcome for parents whose infants were admitted to a neonatal intensive care unit
Roger T Mulder1, Janet D Carter2, Christopher M A Frampton1
1Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.
Insights
Infants admitted to the neonatal intensive care unit (NICU) do not cause long-term psychological distress in parents. Mothers of infants with developmental delays showed a link between psychological distress and child development.
Area of Science:
- Neonatal care
- Parental mental health
- Child development
Background:
- Infants admitted to neonatal intensive care units (NICUs) may impact parental psychological functioning.
- Long-term psychological effects on parents of NICU infants require further investigation.
Purpose of the Study:
- To evaluate the psychological functioning of parents with infants admitted to a neonatal intensive care unit (NICU) over the first two years of the infant's life.
- To assess the relationship between parental psychological distress and infant neurodevelopmental outcomes.
Main Methods:
- Prospective 2-year follow-up study comparing NICU and control families.
- Clinical interviews, psychiatric diagnoses (Mini-International Neuropsychiatric Interview), and validated scales (Edinburgh Post Natal Depression Scale, Hospital Anxiety and Depression Scale) were used to assess psychological distress.
- Infant neurodevelopment was assessed using the Bayley II at 2 years.
Main Results:
- No significant difference in psychological distress was found between NICU parents (30.8%) and control parents (28.2%).
- No relationship was observed between fathers' psychological distress and infant development.
- Mothers' psychological distress was linked to their child's mental development, particularly in cases of severe developmental delay.
Conclusions:
- NICU admission does not appear to cause significant long-term negative psychological effects on parents.
- Interventions for parents should prioritize mothers of infants with potential significant mental health development problems, regardless of NICU admission.
Objective:
To evaluate the psychological functioning in parents whose infants were admitted to a neonatal intensive care unit (NICU) over the first 2 years of the infant's life.
Methods:
Prospective 2-year follow-up study of a random selection of NICU and control families. At baseline, 9 months, and 2 years, all parents received a clinical interview. Infants underwent a pediatric examination and Bayley II neurodevelopmental assessment at 2 years. Psychological distress is defined as having one or more of the following criteria: any psychiatric diagnosis on the Mini-International Neuropsychiatric Interview at 2 years; Edinburgh Post Natal Depression Scale score more than 12.5 at 2 years; Hospital Anxiety and Depression Scale score more than 11.0 at 2 years, receiving treatment with antidepressants/psychotherapy/counselling over the previous 15 months.
Results:
Overall, 300 families of infants admitted to a NICU and 120 control families were approached to take part in the study. There was no difference in psychological distress in NICU parents (30.8%) vs control parents (28.2%). In fathers, there was no relationship between psychological distress and infant development measured using the Bayley II. In mothers, there was a relationship between psychological distress and the child's mental development, which was most significant in infants with severe developmental delay.
Conclusions:
There are no significant long-term negative psychological effects on parents whose infants were admitted to a NICU. Should interventions for parents be offered, they should focus on mothers whose infants are likely to have significant mental health development problems whether or not their infant is admitted to a NICU.
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