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Updated: May 2, 2026

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2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia
Published on: June 22, 2013
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[Pitfall in conservative therapy for working patients with brain ischemia]
Yuichi Aoyama1, Shinsuke Ohta, Saburou Sakaki
1Department of Neurosurgery, and Shiraniwa Hospital.
Journal of UOEH
|March 18, 2014
Summary
Occupational mental stress can increase the risk of gastroduodenal ulcers, potentially leading to recurrent cerebral infarction. Patient
Area of Science:
- Neurology
- Gastroenterology
- Occupational Health
Context:
- A 59-year-old man with symptomatic left middle cerebral artery stenosis declined surgery for conservative management.
- The patient experienced recurrent cerebral infarction, severe anemia, and hypotension due to gastroduodenal ulcer bleeding shortly after retirement.
Purpose:
- To investigate the potential link between occupational mental stress, gastroduodenal ulcers, and recurrent cerebral infarction.
- To highlight the importance of considering a patient's occupational situation in preventing cerebrovascular events.
Summary:
- Recurrent cerebral infarction in the patient was associated with hemodynamic factors and mental stress from a gastroduodenal ulcer, as indicated by MRI.
- Occupational mental stress is a known risk factor for gastroduodenal ulcers, suggesting a connection to the patient's cerebrovascular events.
Impact:
- Emphasizes the role of occupational mental stress as a modifiable risk factor in cerebrovascular disease.
- Suggests integrating occupational assessments into the prevention strategies for cerebral apoplexy.
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