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Updated: May 2, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
De-misty-fying the mesentery: an algorithmic approach to neoplastic and non-neoplastic mesenteric abnormalities
Myles T Taffel1, Nadia J Khati, Nabila Hai
1Department of Radiology, The George Washington University Hospital, 900 23rd St, NW, Washington, DC, 20037, USA, mtaffel@mfa.gwu.edu.
Abstract:
Mesenteric abnormalities are often incidentally discovered on cross-sectional imaging performed during daily clinical practice. Findings can range from the vague "misty mesentery" to solid masses, and the possible etiologic causes encompass a wide spectrum of underlying pathologies including infectious, inflammatory, and neoplastic processes. Unfortunately, the clinical and imaging findings are often non-specific and may overlap. This article discusses the various diseases that result in mesenteric abnormalities. It provides a framework to non-invasively differentiate these entities, when possible.
Insights
Mesenteric abnormalities found on imaging have diverse causes, including infections, inflammation, and tumors. This review offers a framework for differentiating these conditions non-invasively using imaging findings.
Area of Science:
- Radiology
- Gastroenterology
- Pathology
Background:
- Mesenteric abnormalities are frequently incidental findings during cross-sectional imaging.
- These abnormalities present a wide spectrum of potential causes, including infectious, inflammatory, and neoplastic processes.
- Distinguishing between these causes can be challenging due to non-specific clinical and imaging features.
Purpose of the Study:
- To discuss the various diseases that manifest as mesenteric abnormalities.
- To provide a framework for the non-invasive differentiation of these entities based on imaging characteristics.
Main Methods:
- Review of existing literature and clinical case studies.
- Analysis of imaging findings associated with diverse mesenteric pathologies.
- Development of a diagnostic framework based on cross-sectional imaging features.
Main Results:
- Mesenteric abnormalities encompass a broad range of conditions, from "misty mesentery" to solid masses.
- Imaging findings are often non-specific, requiring careful correlation with clinical context.
- A systematic approach can aid in differentiating common causes of mesenteric abnormalities.
Conclusions:
- Mesenteric abnormalities require a comprehensive diagnostic approach.
- Cross-sectional imaging plays a crucial role in identifying and characterizing these abnormalities.
- This framework aims to improve non-invasive differentiation of mesenteric diseases.
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