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Anticancer properties of Monascus metabolites
Tao Yang1, Junwen Liu, Feijun Luo
1aNational Engineering Laboratory for Rice and Byproduct In-depth Processing, Central South University of Forestry and Technology bDepartment of Pathology, College of Medicine, Hunan Normal University, Hunan, China cHerman B Wells Center for Pediatric Research, James Whitcomb Riley Hospital for Children, Indiana University - Purdue University Indianapolis, Indianapolis, Indiana dDepartment of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.
Monascus fermented products show anticancer potential, supported by clinical evidence and research into bioactive components and mechanisms. Future developments aim to create novel food products and pharmaceuticals to reduce cancer incidence and mortality.
Area of Science:
- Food Science
- Pharmacology
- Oncology
Background:
- Monascus fermentation yields products with potential health benefits.
- Anticancer properties of Monascus metabolites are an area of active research.
- Understanding these properties is crucial for developing new therapeutic strategies.
Purpose of the Study:
- To review current knowledge on the anticancer properties of Monascus fermented products.
- To explore clinical evidence, bioactive components, and mechanisms of action.
- To identify challenges and future directions in this field.
Main Methods:
- Comprehensive literature review of studies on Monascus fermented products and their anticancer effects.
- Analysis of clinical evidence, identification of bioactive compounds, and elucidation of anticancer mechanisms.
- Discussion of current limitations and future research perspectives.
Main Results:
- Monascus metabolites exhibit significant anticancer potential.
- Several bioactive components have been identified with specific anticancer activities.
- Mechanisms of action involve various cellular pathways relevant to cancer treatment.
Conclusions:
- Monascus fermented products hold promise as a source of anticancer agents.
- Further research is needed to overcome existing challenges and develop novel applications.
- Advancements could lead to new food products and pharmaceuticals to combat cancer.
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