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Updated: May 2, 2026
10:54
Extraction of Plant-based Capsules for Microencapsulation Applications
Published on: November 9, 2016
11.4K
Hollow pollen shells to enhance drug delivery
Alberto Diego-Taboada1, Stephen T Beckett2, Stephen L Atkin3
1Sporomex Ltd., Newland Avenue, Driffield YO25 6TX, UK. A.D.Taboada@hull.ac.uk.
Pharmaceutics
|March 19, 2014
Summary
Pollen and spore shells are natural microcapsules with unique properties. These sporopollenin microcapsules offer controlled release of actives, showing potential for enhanced nutraceutical and drug delivery systems.
Area of Science:
- Biomaterials Science
- Plant Biology
- Nanotechnology
Background:
- Pollen and spore shells are natural microcapsules protecting plant genetic material.
- Composed of cellulose (intine) and sporopollenin (exine), their proportions vary by species.
- Sporopollenin's structure, containing phenols, provides antioxidant and UV protection.
Purpose of the Study:
- To explore the characteristics and potential applications of pollen and spore-derived microcapsules.
- To investigate their suitability as delivery vehicles for active compounds.
- To understand the mechanisms of controlled release and mucoadhesion.
Main Methods:
- Characterization of sporopollenin microcapsule structure and properties.
- Assessment of encapsulation efficiency and controlled release kinetics.
- Evaluation of mucoadhesion properties for intestinal delivery.
Main Results:
- Microcapsules exhibit homogeneity, resilience to chemicals and heat (up to 250 °C).
- Demonstrated ability to encapsulate and control the release of active substances.
- Mucoadhesion to intestinal tissues suggests prolonged contact and enhanced delivery efficiency.
Conclusions:
- Sporopollenin microcapsules are robust, natural delivery systems.
- Potential for controlled release of nutraceuticals and drugs.
- Further research can optimize their application in pharmaceutical and nutraceutical industries.
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