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Updated: May 2, 2026
07:35
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
6.5K
[Colorectal cancer - review].
Laeknabladid
|March 19, 2014
Summary
Colorectal cancer is a common malignancy, particularly in older adults. Treatment varies by stage, with surgery for localized disease and chemotherapy for advanced or metastatic colorectal cancer, where significant therapeutic advancements are being made.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Oncology
Context:
- Colorectal cancer is the third most prevalent cancer in the Western hemisphere.
- Incidence significantly rises with increasing age.
- A notable percentage of patients (up to 20%) present with metastatic disease, predominantly to the liver.
Purpose:
- To outline the current therapeutic strategies for colorectal and rectal cancers.
- To highlight the role of surgery, chemotherapy, and radiation therapy in managing these malignancies.
- To acknowledge recent progress in treating metastatic colorectal cancer.
Summary:
- Localized colorectal cancer is curable with surgery; adjuvant chemotherapy is recommended for lymph node metastasis.
- Rectal cancer therapy involves surgery, radiation, and chemotherapy.
- Chemotherapy is the primary treatment for advanced colorectal cancer, with surgery offering salvage options for recurrent or metastatic cases.
Impact:
- Informs clinical decision-making for colorectal and rectal cancer treatment.
- Underscores the importance of multimodal therapy based on disease stage.
- Highlights the evolving landscape and progress in managing metastatic colorectal cancer.
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