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[Melioidosis, first four cases in Iceland]

Thorgerdur Gudmundsdottir, Hilmir Asgeirsson, Hordur Snaevar Hardarson

    Laeknabladid
    |March 19, 2014
    PubMed

    Insights

    This study details the first four Melioidosis cases in Iceland, caused by Burkholderia pseudomallei. It highlights the infection

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Clinical Medicine

    Background:

    • Melioidosis is caused by Burkholderia pseudomallei, a Gram-negative bacterium.
    • Geographically, endemic areas include Southeast Asia and Northern Australia.
    • The disease presents with diverse clinical manifestations, not limited to pneumonia.

    Observation:

    • Four cases of Melioidosis treated in Iceland are reported.
    • These cases demonstrate the protean manifestations of the infection.
    • Burkholderia pseudomallei exhibits resistance to common antibiotics and intracellular persistence.

    Findings:

    • Melioidosis can affect nearly every organ system.
    • Laboratory identification of Burkholderia pseudomallei can be challenging.
    • The bacteria pose an infection risk to laboratory personnel.

    Implications:

    • Increased awareness of Melioidosis is crucial, especially in non-endemic regions.
    • Prompt laboratory notification is essential for accurate diagnosis and safety.
    • Prolonged antibiotic therapy is required for successful treatment due to bacterial characteristics.

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