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Cohort profile: project viva.

Emily Oken1, Andrea A Baccarelli2, Diane R Gold2

  • 1Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA emily_oken@hphc.org.

International Journal of Epidemiology
|March 19, 2014
PubMed
Summary
This summary is machine-generated.

Project Viva is a longitudinal study examining prenatal factors and maternal/child health. It tracks health outcomes from pregnancy through mid-childhood, providing valuable data for researchers.

Keywords:
Pregnancychildhoodcohortnutritionobesity

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Area of Science:

  • Environmental Health
  • Epidemiology
  • Developmental Pediatrics

Background:

  • Prenatal exposures significantly influence maternal and child health trajectories.
  • Longitudinal studies are crucial for understanding developmental impacts over time.
  • Project Viva was established to investigate these critical relationships.

Purpose of the Study:

  • To examine the relationship between prenatal diet and other factors with maternal and child health outcomes.
  • To collect comprehensive data on pregnancy, maternal health, and child development.
  • To provide a valuable dataset for researchers investigating environmental and developmental influences on health.

Main Methods:

  • Recruited pregnant women in eastern Massachusetts (1999-2002).
  • Conducted in-person visits during pregnancy, delivery, infancy, early childhood, and mid-childhood.
  • Collected data via interviews, questionnaires, anthropometric/neurodevelopmental assessments, biosamples, and medical records.

Main Results:

  • Enrolled 2341 eligible women, with 2128 live births.
  • 1279 mother-child pairs provided data at the mid-childhood visit.
  • Primary outcomes include pregnancy, maternal cardiometabolic/mental health, and child neurodevelopment, asthma, and obesity.

Conclusions:

  • Project Viva provides a rich, longitudinal dataset on maternal and child health.
  • The study facilitates research into the long-term effects of prenatal and early-life exposures.
  • Data access is available for interested investigators.