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Updated: May 2, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Serum procalcitonin as a predicting value in severity and prognosis of CAP in sickle cell-patients
Abstract:
The Pneumonia Severity Index (PSI) and CURB-65 predict outcomes in community acquired pneumonia but have limitations. The study evaluated if procalcitonin in community-acquired pneumonia provides prognostic information with the PSI and CURB-65 in sickle cell adult patients. Twenty sickle cell positive adult patients with a clinical and radiographic diagnosis of community acquired pneumonia were scored using PSI and CRUB-65, and measured procalcitonin levels. They were 12 female 60% and 8 males 40% with mean of age 46.0 +/- 10.26 and were stratified with PSI, CRUB65 and sampled for procalcitonin level for PSI class I (3) patients 15%, class II (10) patients 50%, class III (3) patients 15%, class IV (one) patient 5% and class V (3) patients 15% with mean of 2.55 +/- 1.276 were CRUB65 0 (2) patients 10% 1 (11) patients 55% two (3) patients 15%, three (4) patients 20% with mean of 1.45 +/- 0.94 proclacitonin >0.25 (8) patients 40% and >0.50 were (12) patients 60% with mean of 1.098 +/- 1.346.
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