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Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest.

Lars Wik1, Jan-Aage Olsen2, David Persse3

  • 1Norwegian Center for Prehospital Emergency Care, Oslo University Hospital, Oslo, Norway.

Resuscitation
|March 20, 2014
PubMed

Insights

Integrated automated load distributing band CPR (iA-CPR) demonstrated statistically equivalent survival to hospital discharge compared to high-quality manual CPR (M-CPR). This finding supports iA-CPR as a viable alternative in out-of-hospital cardiac arrest scenarios.

Area of Science:

  • Emergency Medicine
  • Cardiovascular Research
  • Clinical Trials

Background:

  • Out-of-hospital cardiac arrest (OHCA) remains a leading cause of death.
  • High-quality cardiopulmonary resuscitation (CPR) is critical for patient survival.
  • Automated CPR devices are being developed to improve resuscitation quality.

Purpose of the Study:

  • To compare the efficacy of integrated automated load distributing band CPR (iA-CPR) against high-quality manual CPR (M-CPR).
  • To determine if iA-CPR is equivalent, superior, or inferior to M-CPR in terms of survival to hospital discharge.

Main Methods:

  • A randomized, unblinded, controlled group sequential trial was conducted across multiple international sites.
  • Adult patients with out-of-hospital cardiac arrest of presumed cardiac origin were randomized to receive either iA-CPR or M-CPR after initial manual compressions.
  • The primary outcome was survival to hospital discharge, with CPR quality monitored electronically.

Main Results:

  • The study included 4131 patients (2099 iA-CPR, 2132 M-CPR) after exclusions.
  • Survival to hospital discharge rates were 9.4% for iA-CPR and 11.0% for M-CPR.
  • The adjusted odds ratio for survival to hospital discharge was 1.06 (95% CI 0.83-1.37), indicating equivalence between iA-CPR and M-CPR.

Conclusions:

  • Integrated automated load distributing band CPR (iA-CPR) provides statistically equivalent survival to hospital discharge compared to high-quality manual CPR.
  • iA-CPR can be considered a comparable alternative to M-CPR for improving outcomes in out-of-hospital cardiac arrest.
Abstract

Keywords:
Cardiac arrestCardiopulmonary resuscitationLoad distributing bandSurvival

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