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Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches
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Synthesis of silk-based microcapsules by desolvation and hybridization
Bo Du1, Jingjie Wang, Zhimin Zhou
1Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, 300192, PR China. zhangqiq@126.com zhouzhiminf@126.com.
Abstract:
Single-component porous silk microcapsules were synthesized by the one-step desolvation method using PLGA spheres as sacrificial templates. Subsequently, AuNRs-T5 were utilized to synthesize silk-based hybrid capsules, which not only capped the pores of the shell but also enhanced Raman scattering.

