Related Experiment Video
Updated: May 2, 2026
04:42
Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
1.7K
Fahr's Disease Presenting as Mania: A Case Report
Sheikh Shoib1, Mohammad Maqbool Dar1, Tasleem Arif2
1Department of Psychiatry, GMC Srinagar.
Iranian Journal of Psychiatry and Behavioral Sciences
|March 20, 2014
Summary
Fahr's disease, a rare neurological disorder, can manifest with psychiatric symptoms like mania. This case highlights the importance of considering organic causes for mania in patients with intracranial calcifications.
Area of Science:
- Neurology
- Psychiatry
Background:
- Fahr's disease is a rare neurological disorder characterized by bilateral intracranial calcifications.
- It often presents with diverse neurological and psychiatric symptoms.
Observation:
- A 21-year-old male presented with acute mania, including aggression, talkativeness, restlessness, and insomnia.
- Neurological examination was normal, but mental status examination indicated mania.
Findings:
- Brain imaging revealed symmetrical, extensive calcifications in the basal ganglia and cerebral hemispheres, consistent with Fahr's disease.
- This is the first reported case of mania associated with Fahr's disease in a Kashmiri patient.
Implications:
- This case underscores the necessity of investigating organic etiologies, such as Fahr's disease, in patients presenting with mania.
- Early diagnosis and management with mood stabilizers led to significant behavioral improvement within four weeks.
Related Concept Videos
01:30Bipolar Disorder
1.4K
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
1.4K
01:24Mania and Antimanic Drugs: Overview
800
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
800
01:21Huntington Disease l: Introduction
110
Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show...
110
01:24Parkinson Disease l: Introduction
28
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of...
28
01:28Psychosis and Antipsychotic Drugs: Overview
1.2K
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.2K
01:25Hyperthyroidism I: Introduction
30
Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
30