Related Experiment Video
Updated: May 2, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Optic chiasm involvement on MRI with ethambutol-induced bitemporal hemianopia
Vivian B Osaguona1, James A Sharpe, Samira A Awaji
1Neuro-Ophthalmology Section, Division of Neurology, Departments of Medicine, Ophthalmology and Vision Sciences (VBO, JAS, SAA, ANES) and Medical Imaging (RIF), University Health Network, University of Toronto, Toronto, Ontario, Canada.
Abstract:
While ethambutol optic neuropathy usually causes central or cecocentral scotomas, bitemporal visual field defects also have been reported. The pathogenesis of the bitemporal hemianopia has not been established. This article describes magnetic resonance imaging abnormalities involving the optic chiasm in a patient with bitemporal visual field loss. To our knowledge, these neuroimaging findings have not been previously described in association with ethambutol therapy.

