Ask the Experts: Neuropathic pain from a primary care perspective

Blair H Smith1

  • 1University of Dundee, Mackenzie Building, Ninewells Hospital & Medical School, Kirsty Semple Way, Dundee, DD2 4DB, Scotland, UK. b.h.smith@dundee.ac.uk.

Pain Management
|March 25, 2014
PubMed
Summary

Professor Blair H Smith

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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